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--- shimadzu_nexera_analytical_hplc [2024/10/16 19:48] – created mbates
+++ shimadzu_nexera_analytical_hplc [2026/06/02 20:29] (current) – saejinoh
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 |  **Principal Scientist**        |  **Training and Operations Lead**  |
-|  Morgan Bates         |  Zachary Nett  |
+|  David Fisher         |  Zachary Nett  |
-|  morganbates@ucsb.edu         |  zjnett@ucsb.edu  |
+|  dfisher@ucsb.edu         |  zjnett@ucsb.edu  |
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@@ Line 15: / Line 15: @@
 ===== About =====
-The Genevac EZ-2 4.0 Elite is a high-performance parallel evaporator system designed to efficiently remove solvents from samples through evaporation. It uses advanced vacuum and centrifugal technology to evaporate a wide range of solvents, including volatile organic compounds and aqueous solutions, without overheating or degrading sensitive samples. The EZ-2 Elite features a dry scroll pump and is optimized for removal of even the highest boiling point solvents (> 165 °C), such as DMSO and NMP.
+The Shimadzu Nexera Analytical HPLC system enables the identification and quantification of complex mixtures, while also supporting method development for sample purification on both preparative and semi-preparative scales. Equipped with a 6-way switch valve, the system streamlines the selection between four distinct columns, each offering unique surface chemistry and retention properties. These include C18 columns with 100 and 300 Å pore sizes, a C4 column, and a HILIC column. The system's design also allows for easy eluent interchanges, ensuring flexible adaptation to various purification and characterization requirements. Additionally, it features a dedicated PDA and a single quad LCMS-2050 mass spectrometer, which is capable of both ESI and APCI ionization and covers a mass range of 10-2000 m/z.
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-===== Solvent Guidelines and Sample Holder Options =====
+===== Reference Documentation =====
-**Solvent Compatibility** \\
+{{ :analytical_hplc_manual.pdf | NSF BioPACIFIC MIP Analytical HPLC-MS User Manual}}
-SP Genevac evaporators are robust systems designed to be resistant to the most common solvents and acids used within the chemistry laboratory, including TFA and HCl. **However, the Genevac is not compatible with the following:**\\
-• Carbon disulfide\\
-• Diethyl ether\\
-• 1,2-Dimethoxyethane\\
-• 2-Ethoxyethanol\\
-• Hydrogen cyanide\\
-• Pentane\\
-• Triethylsilane\\
-**Sample formats**
-Sample holders for the following formats are available:\\
-• **Vials:** 40, 30, 20, and 8-mL sizes \\
-• **Test tubes:** 16, 18, and 25-mm diameter and up to 150 mm length \\
-• **Centrifuge tubes:** 50-mL size
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