NSF BioPACIFIC MIP Wiki

A National User Facility Dedicated to Biomaterials

User Tools

Site Tools

Trace:
chemspeed_automated_chemistry_platform

Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revisionPrevious revision
Next revision		Previous revision
chemspeed_automated_chemistry_platform [2024/10/14 20:25] – [About] mbateschemspeed_automated_chemistry_platform [2024/10/14 20:30] (current) – [Detailed Specifications] mbates
Line 25: Line 25:
 Multiple reactor systems are available on the platform: (i) the iSynth, (ii) the glass reactor array, and (iii) the MTP pressure block. The iSynth reactor facilitates thermal reactions in 48 × 8 mL disposable glass vials or photochemical reactions under 365 nm illumination in a 16 × 8 mL disposable format. Once reagents are loaded into the vials, any available MTPs (vial racks) can be transferred to the MTP pressure block reactor, allowing reactions to proceed under high pressure (< 100 bar). The glass reactor array comprises a double-jacketed set of 16-, 8-, or 4-glass reactors, with capacities of 13-, 27-, or 100 mL, respectively, for larger-scale transformations. Agitation across all reactor systems is achieved through shaking. Multiple reactor systems are available on the platform: (i) the iSynth, (ii) the glass reactor array, and (iii) the MTP pressure block. The iSynth reactor facilitates thermal reactions in 48 × 8 mL disposable glass vials or photochemical reactions under 365 nm illumination in a 16 × 8 mL disposable format. Once reagents are loaded into the vials, any available MTPs (vial racks) can be transferred to the MTP pressure block reactor, allowing reactions to proceed under high pressure (< 100 bar). The glass reactor array comprises a double-jacketed set of 16-, 8-, or 4-glass reactors, with capacities of 13-, 27-, or 100 mL, respectively, for larger-scale transformations. Agitation across all reactor systems is achieved through shaking.
  
-Reactions can also be set up in disposable glass vials (available in 33 × 20 mL and 72 × 8 mL sizes), well plates, or 96 × 1 mL shell vials, placed on the heat-cool-shake rack for temperature control and mixing. Additionally, photochemical reactions can be initiated using the LED plate from analytical sciences, which offers 365, 405, and 445 nm light, with other wavelengths available upon request.+Reactions can also be set up in disposable glass vials (available in 33 × 20 mL and 72 × 8 mL arrays), well plates, or (96 × 1 mL) shell vials, placed on the heat-cool-shake rack for temperature control and mixing. Additionally, photochemical reactions can be initiated using the LED plate from analytical sciences, which offers 365, 405, and 445 nm light, with other wavelengths available upon request.
  
 For workflow flexibility, the system supports various post-reaction processes, including filtration, precipitation, solution transfer, and aliquot sampling from reaction mixtures. Sample preparation for subsequent HPLC, NMR, MALDI, or SEC analysis can also be integrated. For workflow flexibility, the system supports various post-reaction processes, including filtration, precipitation, solution transfer, and aliquot sampling from reaction mixtures. Sample preparation for subsequent HPLC, NMR, MALDI, or SEC analysis can also be integrated.
Line 40: Line 40:
 ---- ----
  
-===== Detailed Specifications =====+
chemspeed_automated_chemistry_platform.1728937541.txt.gz · Last modified: 2024/10/14 20:25 by mbates